Monday, October 12, 2026
 
Primate Cognitive Lab
 

Laboratory Manager: Dr. Vahid Sheibani

 

Cognitive neuroscience is a subfield of neuroscience that shares many similarities with psychiatry and psychology. In fact, this branch of neuroscience studies the biological processes underlying human cognition, and one of its most important goals is to find the relationship between different brain structures and the brain's basic executive functions. These executive functions are components of higher cognitive processes such as logic, planning, and problem-solving ability. Understanding the biological mechanisms of cognition and the associated brain regions can help find therapeutic approaches in the management of neurological and neuropsychological disorders. From a neurobiological perspective, human studies rely mostly on non-invasive methods such as brain imaging, which can face limitations such as the number of samples studied, heterogeneity in the coordinates and size of the brain area affected, as well as behavioral heterogeneity and disease history among the subjects studied. Furthermore, it is almost impossible to find a causal relationship between specific neural activity and components of the behavior of interest in a study on humans. Therefore, animal studies that focus on finding the basic neural processes involved in behavior and cognition, as well as understanding the neural mechanisms underlying cognitive and behavioral disorders, can contribute to the emergence of effective therapeutic strategies in the treatment or prevention of diseases such as Parkinson's, Alzheimer's, and addiction in humans. One of the suitable animal models in this field is nonhuman primates, which have many similarities with humans in terms of genealogy. In particular, structural-organizational and functional similarities in the brain can be mentioned. In addition, the relatively advanced cognitive abilities in these animals have made them a suitable model of executive functions of the cognitive subtype associated with the prefrontal cortex.

 

 

Facilities available at the Cognitive Science Center of Kerman University of Medical Sciences (Primate Department):

1- Standard facilities for keeping monkeys, including an experienced person in animal care, regular and standard diet, individual cages, a special quarantine room for newly arrived animals, a special room for trained animals, and facilities for keeping them in the open air

2- Automatic behavioral stations for training various cognitive tests to measure executive functions such as working memory, inhibitory control, and mental flexibility
3- CPP room for behavioral testing of models of addiction to psychotropic drugs and abuse such as morphine, heroin, cocaine, ecstasy, etc.
4- Electrophysiology device manufactured by Blacrock Company, specifically for recording extracellular potentials, as well as an electrophysiology device specifically for brain stimulation in freely moving animals, as well as simultaneous recording of brain signals
 
 
 
Articles published from this laboratory
 
  1. Zarei SA, Sheibani V, Tomaz C, Mansouri FA. The effects of oxytocin on primates’ working memory depend on the emotional valence of contextual factors. Behavioural brain research. 2019;362:82-9.
  2. Zarei SA, Sheibani V, Mansouri FA. Interaction of music and emotional stimuli in modulating working memory in macaque monkeys. American journal of primatology. 2019;81(7):e22999.
  3. Ghasemian S, Vardanjani MM, Sheibani V, Mansouri FA. Color-hierarchies in executive control of monkeys' behavior. American Journal of Primatology. 2021;83(2):e23231.
  4. Ghasemian S, Vardanjani MM, Sheibani V, Mansouri FA. Dimensional bias and adaptive adjustments in inhibitory control of monkeys. Animal Cognition. 2021:1-14.
  5. Vardanjani MM, Ghasemian S, Sheibani V, Mansouri FA. The Effects of Emotional Stimuli and Oxytocin on Inhibition Ability and Response Execution in Macaque Monkeys. Behavioural Brain Research. 2021:113409.